高果糖饮食诱导大鼠产生代谢综合征的初步研究.doc

摘要: 健康大鼠为试验材料，以高果糖饮食喂养大鼠，测定了血清尿酸（SUA）、尿液尿酸（UUA）、血清胰岛素（SI）、尿量（UV）、尿酸排泄分数(Feur)、食物摄入、液体摄入、体重。结果表明，经过8周果糖喂养的大鼠的SUA、SBP、SI、UV、体重、液体摄入均高于控制组，UUA、Feur、食物摄入低于控制组。说明果糖摄入导致了高尿血酸症，引起了肾功能紊乱和代谢综合症   

关键词 果糖;代谢综合症；胰岛素；高尿血酸症;肾功能紊乱;

Abstract: Experiments carried out with Healthy rats, with high fructose-fed rats, determination of serum uric acid ( SUA ), uric acid ( UUA ), serum insulin ( SI ), urine volume ( UV ), fractional excretion of uric acid ( Feur ), fluid intake, body weight, food intake. The results show that, after 8weeks in fructose-fed rats of SUA, SBP, SI, UV, body weight, fluid intake were higher than the control group, UUA, Feur, food intake is lower than the control group. Description of fructose ingestion resulted in a high urinary acid disorder, caused renal dysfunction and metabolic syndrome

Key words  Fructose; Metabolic syndrome；Insulin;Hyperuricemia; Renal dysfunction;