Ti5Sn3催化合成乙酸乙酯的实验研究.doc

摘要：乙酸乙酯是有机合成的重要原料和良好的溶剂，广泛应用于饮料、香料、涂料、粘合剂、增塑剂和医药等工业生产。随着我国化学工业、医药工业和相关产业的高速发展，对乙酸乙酯的消费量也逐年上升。

　　　传统的生产中是以浓硫酸为催化剂来合成乙酸乙酯的，该方法工艺复杂，污染严重。硫酸腐蚀设备，并引起副反应。由于浓硫酸的强氧化作用，反应过程中易发生局部脱水、醚化、碳化等副反应，影响最终产品的质量和原料的利用率。

　　　由于固体酸具有不溶于水、制备方便、污染少、产品分离程序简单等优点。所以本实验利用乙醇和乙酸合成乙酸乙酯的实验体系，以正交试验的方式来优化反应时间、醇酸比、催化剂用量等对反应酯化率的影响，考察Ti5Sn3在此酯化反应中的催化活性。

　　　结果表明Ti5Sn3在此反应模型中，具有较好的催化性能。当醇酸摩尔比为1∶3.6，催化剂用量为0.2000g，80℃回流反应0.5h时，酯化率可达86%以上。Ti5Sn3回收4次后，仍能使反应的酯化率达到73.28％—75.31％。

关键词：Ti5Sn3；催化合成； 酯化率

ABSTRACT：Ethyl acetate is an important raw material and good solvent of organic synthesis,.Ethyl acetate was widely used in beverage,spices,coating,adhesive，plasticizer and medicine and other industrial production. With the high speed development of China's chemical industry,pharmaceutical industry and related industry, the need for ethyl acetate consumption has increased year by year.

   The traditional production of sulfuric acid as catalyst in synthesis of ethyl acetate, this method process was complex, serious pollution. Sulfuric acid corrosion equipment, and cause side effects. Because of the strong sulfuric acid oxidation, the reaction process happens during local dehydration, etherification, carbonization influence side effects, the final product quality and the utilization rate of raw materials.

    Because of solid acid has not soluble in water, preparation convenient, less pollution, product separation process simple, etc. So this experiment using ethanol and acetic acid synthesis of ethyl acetate experimental system, to the way of orthogonal test to optimize the reaction time, alkyd, catalyst dosage of than reaction, the influence of esterification rate Ti5Sn3 investigation in the esterification reaction of catalytic activity.

    The results show that the model Ti5Sn3 reaction, and has a good catalytic performance. When alkyd for 1:3.6 the mole ratio of catalyst, for 0.2000 g, 80 ℃ backflow reaction 0.5 h, esterification rate of 86%. Ti5Sn3 recovery 4 times, can still make the reaction of esterification rate 73.28%-75.31%.

Key words:  Ti5Sn3 ;catalytic synthesis ;esterification;